Hi everone, I'm new to this group and am 6 weeks 5 days pregnant. I was recently hospitalized due to dehydration from HG, put on an IV in the hospital and given zofran, and discharged with a prescription for zofran. the zofran does help a bit, but i was doing research on it and found quite a few forums of. I have been taking zofran 8 mg since 5 weeks. @aacevatt2 Zofran is perfectly safe to take during pregnancy, even early pregnancy.