Extended release tablets (Aplenzin): Initial dose: mg orally once a day in the morning (equivalent to mg bupropion HCl). Maintenance dose: After at least 4 days, the dose may be increased to mg once a day (equivalent to mg bupropion HCl). If there is not adequate improvement after several weeks, the. Bupropion Hcl SR Tablet, Extended Release. Bupropion is an antidepressant used for smoking This medication is used to treat depression.
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